The Efficacy of Medium-Chain Triglyceride on the Prognosis and Outcome of Suspected COVID-19 Outpatients: A Randomized Controlled Trial

Background: The novel coronavirus disease (COVID-19), as a global concern, has affected different economic and social aspects, well health costs in various communities. Finding effective available treatment is an urgent need. A recent study demonstrated that the ketogenic diet (KD) activates innate immunity protective property against virus infection. Accordingly, we conducted this to find effect of oral medium-chain triglyceride (MCT) on COVID-19 its clinical manifestations. Methods: This was randomized trial 195 patients clinically suspected referred infectious clinics Kerman. Patients were randomly assigned into two groups. Control group received standard supportive treatment, recommendation for carbohydrate avoiding modification. intervention all mentioned recommendations beside MCT oil. Patients` symptoms, including body temperature, respiratory rate, pain, dyspnea, recorded checklist analyzed. Results: mean age 37.78±12.42 years 40.81±13.23 controls (P=0.231). had lower duration weakness (P=0.004), pain dyspnea gastrointestinal manifestations (P<0.001), sore throat increased rate high intensity cough (P=0.002). Indeed, weakness, frequency, throat, complications significantly females (P=0.006, P=0.030, P=0.005, P=0.001, respectively). In contrast, males group, such rates, intensity, than those control group. Conclusion: Administration outpatients alleviated symptoms helps them overcome probable morbidity.